Endometrial biopsy is a procedure in which a tissue sample is obtained from the inside lining of the uterus so that it can be checked under a microscope. The tissue is thoroughly examined for any cell abnormalities.

What to Expect:

For the biopsy procedure, you will be asked to lie in the same position you would for a Pap smear. A speculum will be inserted into the vagina and opened slightly, and the cervix will be cleaned with an antiseptic solution. A thin, flexible, plastic tube is gently passed into the uterine cavity; and gentle suction removes a sample of the lining. The sample is sent to the lab to be examined by a pathologist.

During the procedure, you may have some cramping as the sample is collected. Sample collection takes only a few seconds. Be assured we do everything we can to minimize your discomfort. A local anesthetic can be used, but many women would rather skip this step and just complete the biopsy as quickly as possible. Please let us know if you would like to have local anesthesia.

Some women feel tired or crampy after having an endometrial biopsy, and they need to go home and rest for a bit. Please tell us if you need a work or school excuse.

How to Prepare:

• Avoid intercourse or douching for 24 hours before your appointment.
• Take a medication for cramping (800 mg of ibuprofen OR 2 Aleve tablets) about 30 minutes before you arrive for your appointment.
• It's o.k. if you are bleeding when you come in for an endometrial biopsy.